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Mkl1 Antibody (OTI3G7) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI3G7
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

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Mkl1 Antibody (OTI3G7) [Janelia Fluor® 669] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 165-397 of human MKL1(NP_065882) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MRTFA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Mkl1 Antibody (OTI3G7) [Janelia Fluor® 669]

  • AMKL
  • KIAA1438
  • MALSAP and coiled-coil domain
  • megakaryoblastic leukemia (translocation) 1
  • Megakaryoblastic leukemia 1 protein
  • Megakaryocytic acute leukemia protein
  • MKL/myocardin-like protein 1
  • Myocardin-related transcription factor A
  • RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein

Background

MKL1 (megakaryoblastic leukemia 1 protein) was identified as part of a t(1;22) translocation with RBM15 associated with acute megakaryoblastic leukemia. It is a transcriptional coactivator of serum response factor (SRF) that promotes muscle differentiation and also plays a role in promoting maturation of megakaryocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional Mkl1 Products

Array NBP2-72715JF669

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Bioinformatics

Gene Symbol MRTFA