MHC Class I Antibody (2G5)

MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Bovine, Chinese Hamster.

We have publications tested in 1 application: FLOW.

Showing Publications 1 - 3 of 3.

Publications using NB100-65938	Applications	Species
Huang K, Chiang S, Yang P et al. Immunogenic Cell Death by the Novel Topoisomerase I Inhibitor TLC388 Enhances the Therapeutic Efficacy of Radiotherapy Cancers 2021-03-11 [PMID: 33799527] (FLOW, Mouse, Human)	FLOW	Mouse, Human
Del Molino Del Barrio I, Wilkins GC, Meeson A et al. Breast Cancer: An Examination of the Potential of ACKR3 to Modify the Response of CXCR4 to CXCL12. Int J Mol Sci. 2018-11-14 [PMID: 30441765] (FLOW, Chinese Hamster)	FLOW	Chinese Hamster
Jung M, Shin MK, Cha SB et al. Supplementation of dietary germanium biotite enhances induction of the immune responses by foot-and-mouth disease vaccine in cattle BMC Vet Res 2014-08-12 [PMID: 25255918] (FLOW, Bovine) Details: This citation used the FITC version of this antibody.	FLOW	Bovine

Array NB100-65938

• MHC Class I Antibodies
• MHC Class I Lysate