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Mer Antibody (3D07) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC
Clone
3D07
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-94148AF350
Alexa Fluor 405
NB110-94148AF405
Alexa Fluor 488
NB110-94148AF488
Alexa Fluor 532
NB110-94148AF532
Alexa Fluor 594
NB110-94148AF594
Alexa Fluor 647
NB110-94148AF647
Alexa Fluor 700
NB110-94148AF700
Alexa Fluor 750
NB110-94148AF750
Allophycocyanin
NB110-94148APC
Biotin
NB110-94148B
CoraFluor 1
NB110-94148CL1
DyLight 350
NB110-94148UV
DyLight 405
NB110-94148V
DyLight 488
NB110-94148G
DyLight 550
NB110-94148R
DyLight 594
NB110-94148DL594
DyLight 650
NB110-94148C
DyLight 680
NB110-94148FR
DyLight 755
NB110-94148IR
FITC
NB110-94148F
HRP
NB110-94148H
Janelia Fluor 525
NB110-94148JF525
Janelia Fluor 549
NB110-94148JF549
Janelia Fluor 646
NB110-94148JF646
Janelia Fluor 669
NB110-94148JF669
PE
NB110-94148PE
PerCP
NB110-94148PCP
Unconjugated
NB110-94148
mFluor Violet 450 SE
NB110-94148MFV450
mFluor Violet 500 SE
NB110-94148MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-94148
Azide and BSA Free
NB110-94148
Azide and BSA Free
NB110-94148-0.025mg
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Mer Antibody (3D07) [mFluor Violet 610 SE] Summary

Immunogen
Recombinant Mouse Mer extracellular domain
Specificity
It has no cross-reactivity with recombinant mouse Axl or recombinant mouse Dtk.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
MERTK
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Mer Antibody (3D07) [mFluor Violet 610 SE]

  • c-Eyk
  • c-mer proto-oncogene tyrosine kinase
  • C-mer
  • EC 2.7.10
  • EC 2.7.10.1
  • MER receptor tyrosine kinase
  • Mer
  • MerTK
  • MGC133349
  • Receptor tyrosine kinase MerTK
  • RP38Proto-oncogene c-Mer
  • STK kinase
  • tyrosine-protein kinase Mer

Background

MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MERTK