Species: Mu
Applications: Flow, IHC, CyTOF-ready, Dual ISH-IHC
Host: Goat Polyclonal
Species: Hu
Applications: Flow, CyTOF-ready, ELISA(Cap), KO
Host: Mouse Monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready, KO
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Binding Activity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
MerTK (c-mer, Nyk, Eyk) is a tyrosine kinase that belongs to a family of transmembrane receptors (1). MerTk has been implicated in reversible cell growth arrest, survival, proliferation and cell adhesion. Growth arrest specific protein 6 (Gas6) is an activating ligand for MerTK (2-3). MerTK is required for clearance of apoptotic cells by mononuclear phagocytes in mice; with its absence resulting in progressive lupus like autoimmunity (4). Defects in MERTK are a cause of retinitis pigmentosa (RP) (5).
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
Human
Human
Human
Mouse
|
| Product By Gene ID |
10461 |
| Alternate Names |
- c-mer proto-oncogene tyrosine kinase
- c-mer
- EC 2.7.10
- EC 2.7.10.1
- MER receptor tyrosine kinase
- mer
- MER
- MGC133349
- Receptor tyrosine kinase MerTK
- RP38Proto-oncogene c-Mer
- STK kinase
- tyrosine-protein kinase Mer
|
![Flow Cytometry Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_AF591_Flow_Cytometry_12100.jpg)
![Immunohistochemistry Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_AF591_Immunohistochemistry_22755.jpg)
![Dual RNAscope ISH-IHC Compatible Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_AF591_Dual_RNAscope_ISHIHC_23834.jpg)
![Western Blot Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af591_mouse-mer-affinity-purified-polyclonal-ab-4120241049418.jpg)
![Flow Cytometry Mer Antibody (125518) [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_MAB8912_Flow_Cytometry_13084.jpg)
![Flow Cytometry Mer Antibody (125518) [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_MAB8912_Flow_Cytometry_13085.jpg)
![Knockout Validated Mer Antibody (125518) [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_MAB8912_Knockout_Validated_22944.jpg)
![Flow Cytometry Mer Antibody (125518) [Unconjugated]](http://images.novusbio.com/fullsize/mab8912_human-mer-mab-clone-125518-2282024179562.jpg)
![Western Blot Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_AF891_Western_Blot_20027.jpg)
![Knockout Validated Mer Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/Mer_AF891_Knockout_Validated_22993.jpg)
![N/A Mer [Biotin]](http://images.novusbio.com/fullsize2/DATA_Mer_DY6488_ELISA_2164.jpg)
![ELISA Mer [Biotin]](http://images.novusbio.com/fullsize2/dyc891-2_human-total-mer-duoset-ic-elisa-2-plate-elisa-169202091914.jpg)
![N/A Mer [Biotin]](http://images.novusbio.com/fullsize2/DATA_Mer_DY591_ELISA_2141.jpg)
![Binding Activity Mer [Biotin]](http://images.novusbio.com/fullsize2/avi891_recombinant-human-mer-fc-chimera-avi-tag-protein-cf-binding-activity-412022115032.jpg)
![SDS-PAGE Mer [Biotin]](http://images.novusbio.com/fullsize2/avi891_recombinant-human-mer-fc-chimera-avi-tag-protein-cf-sds-page-612202191536.jpg)
![Binding Activity Mer [Unconjugated]](http://images.novusbio.com/fullsize/protein/10515-mr_recombinant-human-mer-his-tag-protein-cf-156202015136.jpg)
![SDS-PAGE Mer [Unconjugated]](http://images.novusbio.com/fullsize/protein/10515-mr_recombinant-human-mer-his-tag-protein-cf-sds-page-1352020155918.jpg)