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ARPP-21 Antibody

Images

 
Immunohistochemistry-Paraffin: ARPP-21 Antibody [NBP1-90096] - Staining of human skeletal muscle shows very weak cytoplasmic positivity in myocytes.
Orthogonal Strategies: Immunohistochemistry-Paraffin: ARPP-21 Antibody [NBP1-90096] - Analysis in human cerebral cortex and prostate tissues. Corresponding ARPP21 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ARPP-21 Antibody [NBP1-90096] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: ARPP-21 Antibody [NBP1-90096] - Staining of human kidney shows no positivity in cells in tubules as expected.
Immunohistochemistry-Paraffin: ARPP-21 Antibody [NBP1-90096] - Staining of human prostate shows no positivity in glandular cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

ARPP-21 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EQGDLNQAIAEEGGTEQETATPENGIVKSESLDEEEKLELQRRLEAQNQERRKSKSGAGKGKLTRSLAVCEESSARPGGESLQDQESIHLQLSSFSSLQEEDKSRKDDSEREKEKDKNKDKTSEKPKIRMLSKDCSQEYT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARPP21
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
ARPP-21 Recombinant Protein Antigen (NBP1-90096PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (88%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for ARPP-21 Antibody

  • 21 kD
  • cAMP-regulated phosphoprotein, 21kDa
  • R3H domain containing 3

Background

Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ARPP21
Entrez
Uniprot