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Melanocortin-3 R/MC3R Antibody (345404) [DyLight 680]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
345404
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3737U-100UG
Alexa Fluor 405
FAB3737V-100UG
Alexa Fluor 488
FAB3737G-100UG
Alexa Fluor 532
FAB3737X
Alexa Fluor 594
FAB3737T-100UG
Alexa Fluor 647
FAB3737R-100UG
Alexa Fluor 700
FAB3737N-100UG
Alexa Fluor 750
FAB3737S-100UG
Allophycocyanin
FAB3737A
Allophycocyanin/Cy7
FAB3737APCCY7
Biotin
FAB3737B
CoraFluor 1
FAB3737CL1
DyLight 350
FAB3737D
DyLight 405
FAB3737E
DyLight 488
FAB3737K
DyLight 550
FAB3737L
DyLight 594
FAB3737M
DyLight 650
FAB3737W
DyLight 755
FAB3737Z
FITC
FAB3737F
HRP
FAB3737H
Janelia Fluor 525
FAB3737JF525
Janelia Fluor 549
FAB3737I
Janelia Fluor 585
FAB3737JF585
Janelia Fluor 635
FAB3737JF635
Janelia Fluor 646
FAB3737J
Janelia Fluor 669
FAB3737JF669
PE
FAB3737P
PE/Atto594
FAB3737PEATT594
PE/Cy5.5
FAB3737PECY55
PE/Cy7
FAB3737PECY7
PerCP
FAB3737C
Unconjugated
MAB3737
mFluor Violet 450 SE
FAB3737MFV450
mFluor Violet 500 SE
FAB3737MFV500
mFluor Violet 610 SE
FAB3737MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3737
Carrier Free
MAB3737
Carrier Free
MAB3737-SP
Carrier Free
FAB3737V-100UG
Carrier Free
FAB3737U-100UG
Carrier Free
FAB3737T-100UG
Carrier Free
FAB3737S-100UG
Carrier Free
FAB3737R-100UG
Carrier Free
FAB3737N-100UG
Carrier Free
FAB3737G-100UG
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Melanocortin-3 R/MC3R Antibody (345404) [DyLight 680] Summary

Immunogen
Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R
Specificity
Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
MC3R
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Melanocortin-3 R/MC3R Antibody (345404) [DyLight 680]

  • BMIQ9
  • MC3
  • MC3R
  • MC3-R
  • melanocortin 3 receptor
  • melanocortin receptor 3
  • Melanocortin-3 R
  • Melanocortin3R
  • Melanocortin-3R
  • OB20
  • Obesity quantitative trait locus
  • OQTL

Background

Melanocortins are ligands for a subgroup of GPCRs positively coupled to Adenylate cylcases, termed as melanocortin receptors (MC1R, MC2R, MC3R, MC4R amd MC5R). These receptors are widely expressed at varied density throughout the body. The MC3R has been widely implicated in inflammation and is also implicated in a role in obesity and metabolism. MC3R KO mice exhibit reduced linear growth and lean mass and are hyperleptinemic and hyperinsulinemic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Antibody
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Bioinformatics

Gene Symbol MC3R