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MCPH1 Antibody (OTI2A3) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI2A3
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

MCPH1 Antibody (OTI2A3) [DyLight 488] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 1-264 of human MCPH1 (NP_078872) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MCPH1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MCPH1 Antibody (OTI2A3) [DyLight 488]

  • BRCT-repeat inhibitor of TERT expression 1
  • BRIT1
  • FLJ12847
  • MCPH1
  • MCT
  • microcephalin 1
  • Microcephalin
  • microcephaly, primary autosomal recessive 1

Background

MCPH-1 was identified in a screen for negative regulators of hTERT (human telomerase) expression. It has been implicated in chromosome condensation and DNA damage induced cellular responses. It may play a role in neurogenesis and regulation of the size of the cerebral cortex. Defects in MCPH1 are the cause of primary microcephaly 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Contact Information

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Bioinformatics

Gene Symbol MCPH1