Home » M-CSFR/CD115 » M-CSFR/CD115 Antibodies » M-CSFR/CD115 Antibody (460615) [Janelia Fluor® 525]
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M-CSFR/CD115 Antibody (460615) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
460615
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3818U-100UG
Alexa Fluor 405
FAB3818V-100UG
Alexa Fluor 488
FAB3818G-100UG
Alexa Fluor 532
FAB3818X
Alexa Fluor 594
FAB3818T-100UG
Alexa Fluor 647
FAB3818R-100UG
Alexa Fluor 700
FAB3818N-100UG
Alexa Fluor 750
FAB3818S-100UG
Allophycocyanin
FAB3818A
Allophycocyanin/Cy7
FAB3818APCCY7
Biotin
FAB3818B
CoraFluor 1
FAB3818CL1
DyLight 350
FAB3818D
DyLight 405
FAB3818E
DyLight 488
FAB3818K
DyLight 550
FAB3818L
DyLight 594
FAB3818M
DyLight 650
FAB3818W
DyLight 680
FAB3818Y
DyLight 755
FAB3818Z
FITC
FAB3818F
HRP
FAB3818H
Janelia Fluor 549
FAB3818I
Janelia Fluor 585
FAB3818JF585
Janelia Fluor 635
FAB3818JF635
Janelia Fluor 646
FAB3818J
Janelia Fluor 669
FAB3818JF669
PE/Atto594
FAB3818PEATT594
PE/Cy5.5
FAB3818PECY55
PE/Cy7
FAB3818PECY7
Phycoerythrin
FAB3818P
Unconjugated
MAB3818
mFluor Violet 450 SE
FAB3818MFV450
mFluor Violet 500 SE
FAB3818MFV500
mFluor Violet 610 SE
FAB3818MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3818
Carrier Free
MAB3818
Carrier Free
FAB3818A
Carrier Free
FAB3818P
Carrier Free
MAB3818-SP
Carrier Free
FAB3818V-100UG
Carrier Free
FAB3818U-100UG
Carrier Free
FAB3818T-100UG
Carrier Free
FAB3818S-100UG
Carrier Free
FAB3818R-100UG
Carrier Free
FAB3818N-100UG
Carrier Free
FAB3818G-100UG
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M-CSFR/CD115 Antibody (460615) [Janelia Fluor® 525] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse M-CSF R/CD115
Ala20-Ser511
Accession # P09581
Specificity
Detects mouse M-CSF R/CD115 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human M-CSF R/CD115, recombinant mouse (rm) PDGF R beta , or rmFlt-3 Ligand is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
CSF1R
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for M-CSFR/CD115 Antibody (460615) [Janelia Fluor® 525]

  • CD115 antigen
  • CD115
  • c-fms
  • colony stimulating factor 1 receptor
  • CSF1R
  • CSF-1-R
  • CSFR
  • EC 2.7.10.1
  • FMS proto-oncogene
  • FMSFIM2
  • macrophage colony stimulating factor I receptor
  • macrophage colony-stimulating factor 1 receptor
  • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • M-CSF R
  • MCSFR
  • M-CSFR
  • Proto-oncogene c-Fms

Background

MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSF1R