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LSD1 Antibody

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Western Blot: LSD1 Antibody [NB100-56475] - Analysis of LSD1 in the 1) absence and 2) presence of immunizing peptide in human brain lysate using this antibody. 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, Pm, ZeSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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LSD1 Antibody Summary

Immunogen
A portion of amino acids 100-150 of human LSD1 was used as the immunogen.
Marker
Nucleus Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM1A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 0.5-2 ug/ml
Control
Human Brain Whole Tissue Lysate (Adult Whole Normal)
Reviewed Applications
Read 1 Review rated 5
using
NB100-56475 in the following application:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.2% gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LSD1 Antibody

  • amine oxidase (flavin containing) domain 2
  • AOF2
  • AOF2lysine-specific histone demethylase 1
  • BHC110
  • BHC110FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
  • Flavin-containing amine oxidase domain-containing protein 2
  • KIAA0601KDM1
  • LSD1
  • LSD1BRAF35-HDAC complex protein BHC110
  • lysine (K)-specific demethylase 1
  • Lysine (K)specific Demethylase 1A
  • Lysine (K)-specific Demethylase 1A
  • lysine-specific histone demethylase 1A

Background

LSD1 is a flavin-containing novel nuclear protein having an N-terminal SWIRM domain and a C-terminal FAD-binding motif and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LSD1 Antibody (NB100-56475) (0)

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Review for LSD1 Antibody (NB100-56475) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB100-56475:
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WB
(1)
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Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
WB Human 01/26/2010
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Summary

ApplicationWestern Blot
Sample TestedHeLa cell lysates, Sample Amount: 50
SpeciesHuman

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Verified Customer
01/26/2010
Application: WB
Species: Human

Bioinformatics

Gene Symbol KDM1A
Entrez
Uniprot