Human CD41+platelets were stained with Mouse Anti-Human LAP (TGF-beta 1) PE-conjugated Monoclonal Antibody (Catalog # FAB2463P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our ...read more
LAP (TGF-beta 1) Antibody (27232) [Phycoerythrin] Summary
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human LAP (TGF-beta 1) Leu30-Arg278 (Cys33Ser) Accession # P01137
Specificity
Detects human LAP (TGF-beta 1) in direct ELISAs. In direct ELISAs, this antibody does not cross-react with recombinant human (rh) TGF‑ beta 1, rhTGF‑ beta 2, rhTGF‑ beta 1.2, rhTGF‑ beta 3, or rhTGF‑ alpha .
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TGFB1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for LAP (TGF-beta 1) Antibody (27232) [Phycoerythrin]
CED
DPD1
LAP (TGFbeta 1)
LAP (TGF-beta 1)
LAP
TGFB
TGFB1
TGFbeta
transforming growth factor beta 1
Background
The TGF‑ beta family includes several related proteins (70‑80% sequence homology) from mammalian, avian, or Xenopus systems that are now designated TGF‑ beta 1, TGF‑ beta 2, TGF‑ beta 1.2, TGF‑ beta 3, TGF‑ beta 4, and TGF‑ beta 5. These proteins are secreted by cells in the form of an inactive complex, referred to as latent TGF-beta , that consists of TGF‑ beta associated non-covalently with a Latency-associated peptide (LAP). These two proteins are synthesized as a single pro-peptide that is cleaved in a post Golgi compartment prior to secretion. Different TGF‑ beta family members are naturally associated with their own distinct LAPs.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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