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Langerin/CD207 Antibody (205C1) [Alexa Fluor® 647]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ICC/IF
Clone
205C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 647

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Langerin/CD207 Antibody (205C1) [Alexa Fluor® 647] Summary

Immunogen
Langerin/CD207 was used as immunogen.
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
CD207
Purity
Ion exchange chromatography
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C in the dark. Avoid freeze-thaw cycles.
Buffer
PBS and 50% Glycerol
Preservative
No Preservative
Purity
Ion exchange chromatography

Notes

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

Alternate Names for Langerin/CD207 Antibody (205C1) [Alexa Fluor® 647]

  • CD207 antigen
  • CD207 antigen, langerin
  • CD207 molecule, langerin
  • CD207
  • CLEC4KLangerhans cell specific c-type lectin
  • C-type lectin domain family 4 member K
  • C-type lectin domain family 4, member K
  • Langerin

Background

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD207