Langerin/CD207 Antibody (205C1) [Alexa Fluor® 647] Summary
Immunogen |
Langerin/CD207 was used as immunogen. |
Isotype |
IgM |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
CD207 |
Purity |
Ion exchange chromatography |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:10-1:1000
- Immunocytochemistry/ Immunofluorescence 1:10-1:2000
|
Packaging, Storage & Formulations
Storage |
Store at -20C in the dark. Avoid freeze-thaw cycles. |
Buffer |
PBS and 50% Glycerol |
Preservative |
No Preservative |
Purity |
Ion exchange chromatography |
Notes
This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.
Alternate Names for Langerin/CD207 Antibody (205C1) [Alexa Fluor® 647]
Background
Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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