KPNA3 Antibody

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IF/IHC, IHC-P, WB.

Showing Publications 1 - 4 of 4.

Publications using NB100-81650	Applications	Species
Gebhardt A, Habjan M, Benda C et al. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun 2015-09-18 [PMID: 26382858] (WB, Human)	WB	Human
Zhang P, Yang X, Ma X et al. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Mol Cancer 2015-01-01 [PMID: 25890085] (IF/IHC)	IF/IHC
Zhang P, Garnett J, Creighton CJ et al. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. J. Pathol. 2014-02-01 [PMID: 24132643] (WB, IHC-P, Human)	WB, IHC-P	Human
Okazaki K, Nakayama N, Nariai Y et al. Nuclear localization signal in a cancer-related transcriptional regulator protein NAC1. Carcinogenesis 2012-10-01 [PMID: 22665369]

Array NB100-81650

• KPNA3 Antibodies
• KPNA3 Lysate
• KPNA3 Proteins