KPNA3 Products

Description

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. [provided by RefSeq]

Bioinformatics

Entrez	16648 Mouse 3839 Human
Uniprot	NM_002267 Human NP_002258 Human NP_002258. Human O00505 Human
Product By Gene ID	3839
Alternate Names	hSRP1 importin alpha 4 Importin alpha Q2 importin alpha-3 importin subunit alpha-3 importin-alpha-Q2 IPOA4 karyopherin alpha 3 (importin alpha 4) Karyopherin subunit alpha-3 qip2 Qip2 QIP2 SRP1 SRP1gamma SRP1-gamma SRP4