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Kallikrein 7 Antibody (KLK7/4692) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
KLK7/4692
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 750

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Kallikrein 7 Antibody (KLK7/4692) [Alexa Fluor® 750] Summary

Immunogen
Recombinant fragment of human Kallikrein 7 protein (around aa 1-200) (exact sequence is proprietary)
Localization
Secreted.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KLK7
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Kallikrein 7 Antibody (KLK7/4692) [Alexa Fluor® 750]

  • EC 3.4.21
  • EC 3.4.21.117
  • hK7
  • hSCCE
  • kallikrein 7 (chymotryptic, stratum corneum)
  • Kallikrein 7
  • kallikrein-related peptidase 7
  • KLK7
  • protease, serine, 6
  • PRSS6
  • SCCEkallikrein-7
  • Serine protease 6
  • signal protein
  • Stratum corneum chymotryptic enzyme

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLK7