ITFG1 Antibody (936213) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Integrin-alpha FG-GAP repeat-containing protein 1 (ITFG1), also known as T cell immunomodulatory protein (TIP), was initially identified using bioinformatics and high-throughput cell-based screening assays to isolate novel factors involved in T cell biology.  A ubiquitously expressed 98 kDa glycoprotein, ITFG1 contains an N-terminal signal peptide and a C-terminal transmembrane domain flanking twelve potential N-linked glycosylation sites.  Human and mouse T cells treated with ITFG1 in vitro secreted the cytokines IFN-g, TNF-a and IL-10, while in vivo ITFG1 was protective in a mouse acute graft-versus-host disease (GVHD) model.  Over amino acids (aa) 1-566, human ITFG1 shares 89% and 88% aa identity with mouse and rat ITFG1, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB89001	Applications	Species
CH Tan, KW Cheng, H Park, PW Sternberg, TF Chou LINKIN-associated proteins necessary for tissue integrity during collective cell migration bioRxiv : the preprint server for biology, 2023-06-11;0(0):. 2023-06-11 [PMID: 36798316] (Flow Cytometry, Western Blot, Human)	Flow Cytometry, Western Blot	Human

Array MAB89001

• ITFG1 Antibodies
• ITFG1 Lysate
• ITFG1 Proteins