IRF4 Antibody (MUM1/8560R) Summary
Description |
Positive Controls: Human tonsil or diffuse large B-cell lymphoma (DLBCL).
Antibody with azide - store at 2 to 8C. Non-hazardous. No MSDS required. |
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
Recombinant fragment (corresponding to C-terminal) of IRF4 protein (exact sequence is proprietary) |
Localization |
Nucleus. |
Isotype |
IgG Kappa |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
IRF4 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry-Paraffin 1-2 ug/ml
|
Application Notes |
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes. at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
10mM PBS with 0.05% BSA |
Preservative |
0.05% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for IRF4 Antibody (MUM1/8560R)
Background
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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