CD79A Antibody (HM57)

A disulfide-linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non-covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Bovine, Canine, Chicken.

We have publications tested in 2 applications: IF/IHC, IHC-P.

Showing Publications 1 - 6 of 6.

Publications using NB100-64347	Applications	Species
Patlin B, Schwerdtfeger L, Tobet S Neuropeptide stimulation of physiological and immunological responses in precision-cut lung slices Physiological reports 2023-11-01 [PMID: 37994278]
Ali M, Abdel Hafez M, Mohamed M. The ameliorating effect of some immune-stimulants on bursal and tracheal lesions of broiler chickens challenged with ND virus JoBAZ 2019-12-01 (IF/IHC, Chicken)	IF/IHC	Chicken
Zhu J, Fan Y, Xiong Y et al. Delineating the dynamic evolution from preneoplasia to invasive lung adenocarcinoma by integrating single-cell RNA sequencing and spatial transcriptomics Experimental & molecular medicine 2022-11-25 [PMID: 36434043] (IF/IHC, Human)	IF/IHC	Human
Badr Y, Noreldin AE, Elewa YHA et al. Cellular infiltration, cytokines, and histopathology of skin lesions associated with different clinical forms and stages of naturally occurring lumpy skin disease in cattle Comparative immunology, microbiology and infectious diseases 2022-10-07 [PMID: 36270050] (IHC-P, Bovine)	IHC-P	Bovine
Lynch TJ, Ahlers BA, Swatek AM Et al. Ferret Lung Transplantation Models Differential Lymphoid Aggregate Morphology Between Restrictive and Obstructive Forms of Chronic Lung Allograft Dysfunction Transplantation 2022-04-20 [PMID: 35442232] Details: Citation using the Texas Red version of this antibody.
Skedsmo FS, Espenes A, Tranulis MA et al. Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D Neuromuscular disorders : NMD 2020-11-26 [PMID: 33334662] (IF/IHC, Canine)	IF/IHC	Canine

Images	Ratings	Applications	Species	Date	Details
	3 reviewed by: Verified Customer	IHC-P	Human	10/13/2023	View Summary Application Immunohistochemistry-Paraffin Sample Tested Tonsil Species Human Lot 162901 Comments Comments Reacts with smooth muscle
	3 reviewed by: Verified Customer	IHC-P	Equine	10/13/2023	View Summary Application Immunohistochemistry-Paraffin Sample Tested Skin Species Equine Lot 162901 Comments Comments Reacted strongly with smooth muscle as well as immune cells.
	3 reviewed by: Verified Customer	IHC-P	Feline	10/13/2023	View Summary Application Immunohistochemistry-Paraffin Sample Tested Skin Species Feline Lot 162901 Comments Comments ***Novus Innovators Program - new species or application used on a primary antibody.*** Reacted with muscle and nucleus. Attempts to limit this labeling resulted in a loss of suspected genuine immunoreactivity as well.
	3 reviewed by: Verified Customer	IHC-P	Canine	10/13/2023	View Summary Application Immunohistochemistry-Paraffin Sample Tested cynomolgus monkey lymph node,Lymph Node Species Canine Lot 162901 Comments Comments Reacts with smooth muscle. Attempts to dilute the antibody to eliminate muscle labeling resulted in a loss of signal in immune cells.
Enlarge	5 reviewed by: Verified Customer	IHC-P	Rat	02/17/2018	View Summary Application Immunohistochemistry-Paraffin Sample Tested Spleen tissue Species Rat Lot 1601 Comments Comments IHC performed on paraffin-embedded alcohol fixed tissue. Antigen retrieval pH6. Dilution: 1:500 and ON incubation at 4°C.
Enlarge	4 reviewed by: Verified Customer	IF	Other	08/15/2012	View Summary Application Immunofluorescence Sample Tested Dog Lymphoma Species Other Lot 1106

Array NB100-64347

• CD79A Antibodies
• CD79A Lysate
• CD79A Protein
• CD79A Proteins and Enzymes