Integrin alpha 5/CD49e Antibody (235112) [mFluor Violet 610 SE] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse Integrin alpha 5/CD49e Phe45-Asn999 (Gln68Glu) Accession # P11688 |
Specificity |
Detects mouse Integrin alpha 5/CD49e in direct ELISAs and Western blots. |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
ITGA5 |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Immunocytochemistry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified from hybridoma culture supernatant |
Notes
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for Integrin alpha 5/CD49e Antibody (235112) [mFluor Violet 610 SE]
Background
CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Integrin alpha 5/CD49e Antibody (FAB1754MFV610) (0)
Secondary Antibodies
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