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Integrin alpha 5/CD49e Antibody (235112) [HRP]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready, ICC/IF
Clone
235112
Clonality
Monoclonal
Host
Rat
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1754U-100UG
Alexa Fluor 405
FAB1754V-100UG
Alexa Fluor 488
FAB1754G-100UG
Alexa Fluor 532
FAB1754X
Alexa Fluor 594
FAB1754T-100UG
Alexa Fluor 647
FAB1754R-100UG
Alexa Fluor 700
FAB1754N-100UG
Alexa Fluor 750
FAB1754S-100UG
Allophycocyanin
FAB1754A
Allophycocyanin/Cy7
FAB1754APCCY7
Biotin
FAB1754B
CoraFluor 1
FAB1754CL1
DyLight 350
FAB1754D
DyLight 405
FAB1754E
DyLight 488
FAB1754K
DyLight 550
FAB1754L
DyLight 594
FAB1754M
DyLight 650
FAB1754W
DyLight 680
FAB1754Y
DyLight 755
FAB1754Z
FITC
FAB1754F
Janelia Fluor 525
FAB1754JF525
Janelia Fluor 549
FAB1754I
Janelia Fluor 646
FAB1754J
Janelia Fluor 669
FAB1754JF669
PE/Atto594
FAB1754PEATT594
PE/Cy5.5
FAB1754PECY55
PE/Cy7
FAB1754PECY7
PerCP
FAB1754C
Unconjugated
MAB1754
mFluor Violet 450 SE
FAB1754MFV450
mFluor Violet 500 SE
FAB1754MFV500
mFluor Violet 610 SE
FAB1754MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1754
Carrier Free
MAB1754
Carrier Free
MAB1754-SP
Carrier Free
FAB1754V-100UG
Carrier Free
FAB1754U-100UG
Carrier Free
FAB1754T-100UG
Carrier Free
FAB1754S-100UG
Carrier Free
FAB1754R-100UG
Carrier Free
FAB1754N-100UG
Carrier Free
FAB1754G-100UG
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Integrin alpha 5/CD49e Antibody (235112) [HRP] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Integrin alpha 5/CD49e
Phe45-Asn999 (Gln68Glu)
Accession # P11688
Specificity
Detects mouse Integrin alpha 5/CD49e in direct ELISAs and Western blots.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
ITGA5
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Integrin alpha 5/CD49e Antibody (235112) [HRP]

  • CD49 antigen-like family member E
  • CD49e antigen
  • CD49e
  • Fibronectin receptor subunit alpha
  • fibronectin receptor, alpha subunit
  • FNRAVLA5A
  • Integrin alpha 5
  • integrin alpha-5
  • Integrin alpha-F
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
  • ITGA5
  • very late activation protein 5, alpha subunit
  • VLA-5 alpha
  • VLA-5

Background

CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGA5