Home » IL-3R alpha/CD123 » IL-3R alpha/CD123 Antibodies » IL-3R alpha/CD123 Antibody (32703) [CoraFluor™ 1]
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IL-3R alpha/CD123 Antibody (32703) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, B/N, CyTOF-ready, ICC/IF
Clone
32703
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB301U-100UG
Alexa Fluor 405
FAB301V-100UG
Alexa Fluor 488
FAB301G
Alexa Fluor 532
FAB301X
Alexa Fluor 594
FAB301T-100UG
Alexa Fluor 647
FAB301R-100UG
Alexa Fluor 700
FAB301N
Alexa Fluor 750
FAB301S-100UG
Allophycocyanin
FAB301A
Allophycocyanin/Cy7
FAB301APCCY7
Biotin
FAB301B
DyLight 350
FAB301D
DyLight 405
FAB301E
DyLight 488
FAB301K
DyLight 550
FAB301L
DyLight 594
FAB301M
DyLight 650
FAB301W
DyLight 680
FAB301Y
DyLight 755
FAB301Z
FITC
FAB301F
HRP
FAB301H
Janelia Fluor 525
FAB301JF525
Janelia Fluor 549
FAB301I
Janelia Fluor 585
FAB301JF585
Janelia Fluor 635
FAB301JF635
Janelia Fluor 646
FAB301J
Janelia Fluor 669
FAB301JF669
PE/Atto594
FAB301PEATT594
PE/Cy5.5
FAB301PECY55
PE/Cy7
FAB301PECY7
PerCP (Peridinin-chlorophyll Protein Complex)
FAB301C
Phycoerythrin
FAB301P
Unconjugated
MAB301-100
mFluor Violet 450 SE
FAB301MFV450
mFluor Violet 500 SE
FAB301MFV500
mFluor Violet 610 SE
FAB301MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB301-100
Carrier Free
FAB301C
Carrier Free
FAB301P
Carrier Free
FAB301A
Carrier Free
FAB301G
Carrier Free
FAB301N
Carrier Free
MAB301-SP
Carrier Free
MAB301-100
Carrier Free
MAB301-500
Carrier Free
FAB301V-100UG
Carrier Free
FAB301U-100UG
Carrier Free
FAB301T-100UG
Carrier Free
FAB301S-100UG
Carrier Free
FAB301R-100UG
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IL-3R alpha/CD123 Antibody (32703) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑3 R alpha /CD123
Lys20-Arg305, predicted
Accession # P26951
Specificity
Detects human IL‑3 R alpha /CD123 in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL3RA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Immunohistochemistry
  • Neutralization
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for IL-3R alpha/CD123 Antibody (32703) [CoraFluor™ 1]

  • CD123 antigen
  • CD123
  • hIL3Ra
  • hIL-3Ra
  • IL-3 R alpha
  • IL-3 receptor subunit alpha
  • IL3R alpha
  • IL-3R alpha
  • IL-3R subunit alpha
  • IL3R
  • IL3RA
  • IL-3Ra
  • IL-3R-alpha
  • IL3RAY
  • IL3RX
  • IL3RY
  • interleukin 3 receptor, alpha (low affinity)
  • interleukin-3 receptor subunit alpha
  • MGC34174

Background

IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL3RA