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IGSF1 Antibody

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Independent Antibodies: Immunohistochemistry-Paraffin: IGSF1 Antibody [NBP2-14119] - Staining of human liver, lymph node, pituitary gland and testis using Anti-IGSF1 antibody NBP2-14119 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: IGSF1 Antibody [NBP2-14119] - Staining of human liver.
Immunohistochemistry-Paraffin: IGSF1 Antibody [NBP2-14119] - Staining of human pituitary gland shows strong membranous positivity in cells in anterior lobe.
Immunohistochemistry-Paraffin: IGSF1 Antibody [NBP2-14119] - Staining of human testis.
Immunohistochemistry-Paraffin: IGSF1 Antibody [NBP2-14119] - Staining of human lymph node.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

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IGSF1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the amino acids: IVMPTPKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGTGWIATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSE
Predicted Species
Mouse (99%), Rat (97%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IGSF1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
IGSF1 Recombinant Protein Antigen (NBP2-14119PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for IGSF1 Antibody

  • CHTE
  • IGCD1
  • IGDC1
  • IGDC1Pituitary gland-specific factor 2
  • IGSF1
  • immunoglobulin superfamily member 1
  • immunoglobulin superfamily, member 1
  • Immunoglobulin-like domain-containing protein 1
  • InhBP
  • Inhibin-binding protein
  • KIAA0364p120
  • MGC75490
  • p120
  • PGSF2
  • PGSF2IGCD1

Background

IGSF1 is a gene that codes for a protein that works as a coreceptor in inhibin signaling and antagonizes activing A signaling and is necessary to control the effect of inhibin B during transcription, and is expressed highly in the pancreas, testis, and fetal liver, with a weaker expression in the heart, prostate, and small intestine. There are four isoforms of IGSF1, with lengths of 1336, 1327, 242, and 1341 amino acids and weights of approximately 149, 148, 27 and 149 kDa respectively. Current studies are being done on several disorders and diseases related to this gene including subacute sclerosing panencephalitis, Gaucher's disease, and prostatitis. IGSF1 has also been shown to have interactions with HECTD1, RANBP10, IGF1, ACVR1, and ACVR1B in pathways such as the signal transduction of Activin A pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IGSF1