IGSF1 Products

Description

IGSF1 is a gene that codes for a protein that works as a coreceptor in inhibin signaling and antagonizes activing A signaling and is necessary to control the effect of inhibin B during transcription, and is expressed highly in the pancreas, testis, and fetal liver, with a weaker expression in the heart, prostate, and small intestine. There are four isoforms of IGSF1, with lengths of 1336, 1327, 242, and 1341 amino acids and weights of approximately 149, 148, 27 and 149 kDa respectively. Current studies are being done on several disorders and diseases related to this gene including subacute sclerosing panencephalitis, Gaucher's disease, and prostatitis. IGSF1 has also been shown to have interactions with HECTD1, RANBP10, IGF1, ACVR1, and ACVR1B in pathways such as the signal transduction of Activin A pathway.

Bioinformatics

Entrez	209268 Mouse 3547 Human
Uniprot	NP_001546 Human NP_991402.1 Human Q8N6C5 Human
Product By Gene ID	3547
Alternate Names	IGDC1Pituitary gland-specific factor 2 IgSF1 immunoglobulin superfamily member 1 immunoglobulin superfamily, member 1 Immunoglobulin-like domain-containing protein 1 InhBP INHBP Inhibin-binding protein KIAA0364p120 MGC75490 PGSF2IGCD1