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IGF-I R/IGF1R Antibody (1H7) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC
Clone
1H7
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-66537AF350
Alexa Fluor 405
NB100-66537AF405
Alexa Fluor 488
NB100-66537AF488
Alexa Fluor 532
NB100-66537AF532
Alexa Fluor 594
NB100-66537AF594
Alexa Fluor 647
NB100-66537AF647
Alexa Fluor 700
NB100-66537AF700
Alexa Fluor 750
NB100-66537AF750
Allophycocyanin
NB100-66537APC
Allophycocyanin/Cy7
NB100-66537APCCY7
Biotin
NB100-66537B
DyLight 350
NB100-66537UV
DyLight 405
NB100-66537V
DyLight 488
NB100-66537G
DyLight 550
NB100-66537R
DyLight 594
NB100-66537DL594
DyLight 650
NB100-66537C
DyLight 680
NB100-66537FR
DyLight 755
NB100-66537IR
FITC
NB100-66537F
HRP
NB100-66537H
Janelia Fluor 525
NB100-66537JF525
Janelia Fluor 549
NB100-66537JF549
Janelia Fluor 585
NB100-66537JF585
Janelia Fluor 635
NB100-66537JF635
Janelia Fluor 646
NB100-66537JF646
Janelia Fluor 669
NB100-66537JF669
PE
NB100-66537PE
PE/Atto594
NB100-66537PEATT594
PE/Cy5.5
NB100-66537PECY55
PE/Cy7
NB100-66537PECY7
PerCP
NB100-66537PCP
Unconjugated
NB100-66537
mFluor Violet 450 SE
NB100-66537MFV450
mFluor Violet 500 SE
NB100-66537MFV500
mFluor Violet 610 SE
NB100-66537MFV610
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IGF-I R/IGF1R Antibody (1H7) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Purified human placental IGF-I receptor
Specificity
NB100-66537 recognizes human CD221
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF1R
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reacts with Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for IGF-I R/IGF1R Antibody (1H7) [CoraFluor™ 1]

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Mu
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Bioinformatics

Gene Symbol IGF1R