Recombinant Mouse IFN-gamma Protein

Interferon-gamma (IFN-gamma), also known as Type II interferon or immune interferon, is a cytokine produced primarily by Tlymphocytes and natural killer cells. The protein shares no significant homology with IFN-beta or the various IFN-alpha family proteins. Mature IFN-gamma exists as noncovalently-linked homodimers. It shares high sequence indentity with rat IFN-gamma (86 %). IFN-gamma was originally characterized based on its antiviral activities. The protein also exerts antiproliferative, immunoregulatory and proinflammatory activities and is thus important in host defense mechanisms. IFN-gamma induces the production of cytokines, upregulates the expression of class I and II MHC antigens, Fc receptor and leukocyte adhesion molecules. It modulates macrophage effector functions, influences isotype switching and potentiates the secretion of immunoglobulins by B cells. Additionally, IFN-gamma augments TH1 cell expansion and may be required for TH1 cell differentiation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 4 of 4.

Publications using NBP2-35071	Applications	Species
Jang D, Yang B, You M et al. Fluoxetine decreases phagocytic function via REV-ERB alpha in microglia Research Square 2022-07-05 [PMID: 36048349]
Agharahimi M, Badisa RB, Mazzio E et al. Cocaine potentiates an inflammatory response in C6 astroglia like cells Biomedical reports 2021-05-01 [PMID: 33786174]
Rahman MT, Muppala S, Wu J et al. Effects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages Cell Death Dis 2020-01-23 [PMID: 31974349] (WB, Mouse)	WB	Mouse
Segura-Bayona S, Villamor-Paya M, Attolini CSO Effect of Thrombospondin-4 on Pro-inflammatory Phenotype Differentiation and Apoptosis in Macrophages Peptides 1990-05-01 [PMID: 1974349]

Array NBP2-35071

• IFN-gamma Antibodies
• IFN-gamma Antibody Pairs
• IFN-gamma ELISA Kits
• IFN-gamma Kits
• IFN-gamma Lysate
• IFN-gamma Proteins
• IFN-gamma ELISAs
• IFN-gamma Proteins and Enzymes