Human Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 14. Show All 14 Publications. Collapse Publications.

Publications using DY1826	Applications	Species
Han, X;Liu, L;Huang, S;Xiao, W;Gao, Y;Zhou, W;Zhang, C;Zheng, H;Yang, L;Xie, X;Liang, Q;Tu, Z;Yu, H;Fu, J;Wang, L;Zhang, X;Qian, L;Zhou, Y; RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis Nature communications 2023-11-13 [PMID: 37957139] (Human)		Human
S Meron-Suda, A Reizis, S Goren, A Bialik, A Hochberg, D Cohen Pentraxin 3 and Shigella LPS and IpaB Antibodies Interplay to Defeat Shigellosis Journal of Clinical Medicine, 2022-07-28;11(15):. 2022-07-28 [PMID: 35956001] (Human)		Human
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
N Hwang, MY Kwon, JM Woo, SW Chung Oxidative Stress-Induced Pentraxin 3 Expression Human Retinal Pigment Epithelial Cells is Involved in the Pathogenesis of Age-Related Macular Degeneration Int J Mol Sci, 2019-11-29;20(23):. 2019-11-29 [PMID: 31795454] (Human)		Human
ME O'Brien, D Chandra, RC Wilson, CM Karoleski, CR Fuhrman, JK Leader, J Pu, Y Zhang, A Morris, S Nouraie, J Bon, Z Urban, FC Sciurba Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers Respir. Res., 2019-06-24;20(1):128. 2019-06-24 [PMID: 31234847] (Human)		Human
K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri? Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes J. Leukoc. Biol., 2019-04-01;0(0):. 2019-04-01 [PMID: 30934147] (Human)		Human
NV Batista, M Barbagallo, VLS Oliveira, T Castro-Gom, RDR Oliveira, P Louzada-Ju, GRC Pinheiro, A Mantovani, MM Teixeira, C Garlanda, FA Amaral The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals J. Immunol., 2019-02-04;0(0):. 2019-02-04 [PMID: 30718300] (Human)		Human
V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection PLoS Pathog., 2018-12-07;14(12):e1007469. 2018-12-07 [PMID: 30532257] (Human)		Human
T Akhter, AK Wikström, M Larsson, A Larsson, G Wikström, T Naessen Serum Pentraxin 3 is associated with signs of arterial alteration in women with preeclampsia Int. J. Cardiol., 2017-03-24;0(0):. 2017-03-24 [PMID: 28377191] (Human)		Human
Narae Hwang Tunicamycin-induced Endoplasmic Reticulum Stress Upregulates the Expression of Pentraxin 3 in Human Retinal Pigment Epithelial Cells Korean J Ophthalmol, 2016-12-06;30(6):468-478. 2016-12-06 [PMID: 27980366] (Human)		Human
Foo , Suan-Sin, Chen , Weiqiang, Taylor , Adam, Sheng , Kuo-Chin, Yu , Xing, Teng , Terk-Shi, Reading , Patrick, Blanchard , Helen, Garlanda , Cecilia, Mantovani , Alberto, Ng , Lisa F P, Herrero , Lara J, Mahalingam , Suresh Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. PLoS Pathog, 2015-02-19;11(2):e1004649. 2015-02-19 [PMID: 25695775] (Human)		Human
Ketter P, Guentzel M, Schaffer B, Herzig M, Wu X, Montgomery R, Parida B, Fedyk C, Yu J, Jorgensen J, Chambers J, Cap A, Arulanandam B Severe Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3. Infect Immun, 2014-07-07;82(9):3910-8. 2014-07-07 [PMID: 25001601] (Mouse)		Mouse
Witasp A, Carrero J, Michaelsson K, Ahlstrom H, Kullberg J, Adamsson V, Riserus U, Larsson A, Helmersson-Karlqvist J, Lind L, Stenvinkel P, Arnlov J Inflammatory biomarker pentraxin 3 (PTX3) in relation to obesity, body fat depots and weight loss. Obesity (Silver Spring), 2014-01-25;22(5):1373-9. 2014-01-25 [PMID: 24415446] (Human)		Human
D'Angelo C, D'Angelo C, De Luca A, Zelante T, Bonifazi P, Moretti S, Giovannini G, Iannitti RG, Zagarella S, Bozza S, Campo S, Salvatori G, Romani L Exogenous pentraxin 3 restores antifungal resistance and restrains inflammation in murine chronic granulomatous disease. J. Immunol., 2009-09-04;183(7):4609-18. 2009-09-04 [PMID: 19734205] (Human)		Human
Show All 14 Publications. Collapse Publications.

Array DY1826

• Pentraxin 3/TSG-14 Antibodies
• Pentraxin 3/TSG-14 Antibody Pair
• Pentraxin 3/TSG-14 Proteins
• Pentraxin 3/TSG-14 ELISAs
• Pentraxin 3/TSG-14 Proteins and Enzymes