Name: Human IL-12/IL-23 p40 Quantikine ELISA Kit
Brand: Novus Biologicals
SKU: DP400
Price: 635 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	ELISA
Conjugate	HRP

Catalog# & Conjugate	Size	Price
HRP SP400

HRP PDP400

Conjugate	Catalog #	Availability	Size	Price
HRP	SP400
HRP	PDP400

Background	The Quantikine Human IL-12 p40 Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure IL-12 p40 in cell culture supernates, serum, and plasma. It contains recombinant human IL-12 p40 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant human IL-12 p40. Results obtained using natural human IL-12 p40 showed d...ose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-12 p40. Show More
Specificity	Natural and recombinant human IL-12 p40
Source	N/A
Assay Type	Solid Phase Sandwich ELISA
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details
Gene	IL12B

Human IL-12/IL-23 p40 Quantikine ELISA Kit

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Human IL-12/IL-23 p40 Quantikine ELISA Kit Summary

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Publications for IL-12/IL-23 p40 (DP400)(28)

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Bioinformatics

Publications using DP400	Applications	Species
B Orts, A Gutierrez, L Madero, L Sempere, R Frances, P Zapater Clinical and Immunological Factors Associated with Recommended Trough Levels of Adalimumab and Infliximab in Patients with Crohn's Disease Frontiers in Pharmacology, 2022-01-03;12(0):795272. 2022-01-03 [PMID: 35046819] (Human)		Human
L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 2020-09-14;26(0):428-434. 2020-09-14 [PMID: 33992278] (Human)		Human
J Banga, D Srinivasan, CC Sun, CD Thompson, F Milletti, KS Huang, S Hamilton, S Song, AF Hoffman, YG Qin, B Matta, M LaPan, Q Guo, G Lu, D Li, H Qian, DR Bolin, L Liang, C Wartchow, J Qiu, M Downing, S Narula, N Fotouhi, JA DeMartino, SL Tan, G Chen, BJ Barnes Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization Sci Adv, 2020-05-15;6(20):eaay1057. 2020-05-15 [PMID: 32440537] (Human)		Human
MH Abumaree, E Bahattab, A Alsadoun, A Al Dosaima, FM Abomaray, T Khatlani, B Kalionis, MF El-Muzaini, AO Alawad, AS AlAskar Characterization of the interaction between human decidua parietalis mesenchymal stem/stromal cells and natural killer cells Stem Cell Res Ther, 2018-04-12;9(1):102. 2018-04-12 [PMID: 29650045] (Human)		Human
K Gonda, M Shibata, T Ohtake, Y Matsumoto, K Tachibana, N Abe, H Ohto, K Sakurai, S Takenoshit Myeloid-derived suppressor cells are increased and correlated with type 2 immune responses, malnutrition, inflammation, and poor prognosis in patients with breast cancer Oncol Lett, 2017-06-02;14(2):1766-1774. 2017-06-02 [PMID: 28789407] (Human)		Human
H Shinohara, Y Kuranaga, M Kumazaki, N Sugito, Y Yoshikawa, T Takai, K Taniguchi, Y Ito, Y Akao Regulated Polarization of Tumor-Associated Macrophages by miR-145 via Colorectal Cancer-Derived Extracellular Vesicles J. Immunol., 2017-07-10;0(0):. 2017-07-10 [PMID: 28696255] (Human)		Human
Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan K, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis. PLoS ONE, 2015-03-23;10(3):e0119981. 2015-03-23 [PMID: 25799392] (Human)		Human
Lees J, Duffy S, Perera C, Moalem-Taylor G Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury. Cytokine, 2014-11-20;71(2):207-14. 2014-11-20 [PMID: 25461400] (Human)		Human
Abdi K, Singh N, Spooner E, Kessler B, Radaev S, Lantz L, Xiao T, Matzinger P, Sun P, Ploegh H Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly. J Immunol, 2014-05-12;192(12):6028-36. 2014-05-12 [PMID: 24821971] (Mouse)		Mouse
Loubaki L, Hadj-Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, Aoudjit F, Chakir J Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature. PLoS ONE, 2013-12-05;8(12):e81983. 2013-12-05 [PMID: 24349168] (Human)		Human
Chase JC, Celli J, Bosio CM Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect. Immun., 2008-11-03;77(1):180-95. 2008-11-03 [PMID: 18981246] (Human)		Human
Wang D, Drenker M, Eiz-Vesper B, Werfel T, Wittmann M Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus. Arthritis Rheum., 2008-10-01;58(10):3205-15. 2008-10-01 [PMID: 18821674] (Human)		Human
Alvarado-Navarro A, Montoya-Buelna M, Munoz-Valle JF, Lopez-Roa RI, Guillen-Vargas C, Fafutis-Morris M The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico. Immunol. Lett., 2008-04-28;118(2):148-51. 2008-04-28 [PMID: 18485489] (Human)		Human
Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 2008-04-01;38(4):1012-23. 2008-04-01 [PMID: 18350544] (Human)		Human
Dudek AZ, Yunis C, Harrison LI, Kumar S, Hawkinson R, Cooley S, Vasilakos JP, Gorski KS, Miller JS First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer. Clin. Cancer Res., 2007-12-01;13(23):7119-25. 2007-12-01 [PMID: 18056192] (Human)		Human
Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J. Leukoc. Biol., 2007-11-30;83(3):774-84. 2007-11-30 [PMID: 18055568] (Human)		Human
Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine, 2007-10-29;40(2):128-34. 2007-10-29 [PMID: 17911026] (Human)		Human
Lin YL, Liang YC, Chiang BL Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J. Leukoc. Biol., 2007-08-30;82(6):1473-80. 2007-08-30 [PMID: 17761954] (Human)		Human
Pockros PJ, Guyader D, Patton H, Tong MJ, Wright T, McHutchison JG, Meng TC Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies. J. Hepatol., 2007-05-04;47(2):174-82. 2007-05-04 [PMID: 17532523] (Human)		Human
Lepej SZ, Misic-Majerus L, Jeren T, Rode OD, Remenar A, Sporec V, Vince A Chemokines CXCL10 and CXCL11 in the cerebrospinal fluid of patients with tick-borne encephalitis. Acta Neurol. Scand., 2007-02-01;115(2):109-14. 2007-02-01 [PMID: 17212614] (Human)		Human
Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways. Exp. Hematol., 2006-08-01;34(8):1115-24. 2006-08-01 [PMID: 16863919] (Human)		Human
Vaknin-Dembinsky A, Balashov K, Weiner HL IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J. Immunol., 2006-06-15;176(12):7768-74. 2006-06-15 [PMID: 16751425] (Human)		Human
Spensieri F, Fedele G, Fazio C, Nasso M, Stefanelli P, Mastrantonio P, Ausiello CM Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction. Infect. Immun., 2006-05-01;74(5):2831-8. 2006-05-01 [PMID: 16622221] (Human)		Human
Chapgier A, Wynn RF, Jouanguy E, Filipe-Santos O, Zhang S, Feinberg J, Hawkins K, Casanova JL, Arkwright PD Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo. J. Immunol., 2006-04-15;176(8):5078-83. 2006-04-15 [PMID: 16585605] (Human)		Human
Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. J. Neuroimmunol., 2006-03-29;175(1):169-75. 2006-03-29 [PMID: 16574246] (Human)		Human
Bouchama A, Ollivier V, Roberts G, Al Mohanna F, de Prost D, Eldali A, Saussereau E, El-Sayed R, Chollet-Martin S Experimental heatstroke in baboon: analysis of the systemic inflammatory response. Shock, 2005-10-01;24(4):332-5. 2005-10-01 [PMID: 16205317] (Primate - Papio hamadryas (Hamadyras Baboon))		Primate - Papio hamadryas (Hamadyras Baboon)
Jensen J, Krakauer M, Sellebjerg F Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b. Cytokine, 2005-01-07;29(1):24-30. 2005-01-07 [PMID: 15579375] (Human)		Human
Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection. J. Immunol., 2002-12-01;169(11):6361-8. 2002-12-01 [PMID: 12444143] (Human)		Human
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