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Human IL-12/IL-23 p40 DuoSet ELISA, 15 Plate

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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Human IL-12/IL-23 p40 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
IL12B

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY1240.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-12/IL-23 p40 DuoSet ELISA, 15 Plate

  • CLMF p40
  • CLMF
  • CLMF2
  • Cytotoxic lymphocyte maturation factor 40 kDa subunit
  • IL12 p40
  • IL-12 p40
  • IL-12 subunit p40
  • IL12B
  • IL-12B
  • IL-12BNK cell stimulatory factor chain 2
  • interleukin 12, p40
  • interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocytematuration factor 2, p40)
  • interleukin-12 beta chain
  • interleukin-12 subunit beta
  • natural killer cell stimulatory factor, 40 kD subunit
  • NKSF
  • NKSF2
  • NKSF2IL12, subunit p40

Background

Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.

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Publications for IL-12/IL-23 p40 (DY1240)(31)

We have publications tested in 2 confirmed species: Human, Mouse.


Filter By Application
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Filter By Species
Human
(29)
Mouse
(1)
All Species
Showing Publications 1 - 10 of 31. Show All 31 Publications.
Publications using DY1240 Applications Species
K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 2022-12-23;24(1):. 2022-12-23 [PMID: 36613673] (Human) Human
LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 2022-07-20;12(1):12448. 2022-07-20 [PMID: 35859154] (Human) Human
B van der Lu, MCP Vos, M Grootte Br, N Ijssennagg, F Vrieling, J Meijerink, WT Steegenga The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model Heliyon, 2022-02-02;8(2):e08883. 2022-02-02 [PMID: 35169646] (Human) Human
T Katopodi, S Petanidis, K Domvri, P Zarogoulid, D Anestakis, C Charalampi, D Tsavlis, C Bai, H Huang, L Freitag, W Hohenforst, D Matthaios, K Porpodis Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit Scientific Reports, 2021-07-29;11(1):15455. 2021-07-29 [PMID: 34326381] (Human) Human
AL Martel, NL Fraleigh, E Picard, JD Lewicky, G Pawelec, H Lee, GW Ma, L Mousavifar, R Roy, HT Le Novel immunomodulatory properties of low dose cytarabine entrapped in a mannosylated cationic liposome International journal of pharmaceutics, 2021-07-01;0(0):120849. 2021-07-01 [PMID: 34216770] (Human) Human
S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019-05-13;0(0):. 2019-05-13 [PMID: 31002437] (Human) Human
L Su, P Pan, P Yan, Y Long, X Zhou, X Wang, R Zhou, B Wen, L Xie, D Liu Role of vimentin in modulating immune cell apoptosis and inflammatory responses in sepsis Sci Rep, 2019-04-05;9(1):5747. 2019-04-05 [PMID: 30952998] (Human) Human
C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis Mol. Cancer, 2019-03-30;18(1):64. 2019-03-30 [PMID: 30927925] (Human) Human
A Islam, I Urbarova, JA Bruun, I Martinez-Z Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells Eur Cell Mater, 2019-02-20;37(0):153-174. 2019-02-20 [PMID: 30785213] (Human) Human
MH Kubala, V Punj, VR Placencio-, H Fang, GE Fernandez, R Sposto, YA DeClerck Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer Cell Rep, 2018-11-20;25(8):2177-2191.e7. 2018-11-20 [PMID: 30463014] (Human) Human
Show All 31 Publications.

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Bioinformatics

Gene Symbol IL12B