Human IGFBP-4 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 4 of 4.

Publications using DY804	Applications	Species
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
Weimer A, Madry H, Venkatesan JK Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis. Mol. Med., 2012-05-09;18(1):346-58. 2012-05-09 [PMID: 22160392] (Human)		Human
Wang TH, Chang CL, Wu HM, Chiu YM, Chen CK, Wang HS Insulin-like growth factor-II (IGF-II), IGF-binding protein-3 (IGFBP-3), and IGFBP-4 in follicular fluid are associated with oocyte maturation and embryo development. Fertil. Steril., 2006-11-01;86(5):1392-401. 2006-11-01 [PMID: 17070193] (Human)		Human
Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells. Glia, 2006-06-01;53(8):845-57. 2006-06-01 [PMID: 16586492] (Human)		Human

Array DY804

• IGFBP-4 Antibodies
• IGFBP-4 ELISA Kits
• IGFBP-4 Lysate
• IGFBP-4 Proteins
• IGFBP-4 ELISA
• IGFBP-4 Proteins and Enzymes