Human Cochlin DuoSet ELISA, 5 Plate Summary
| Source |
N/A |
| Assay Type |
Solid Phase Sandwich ELISA |
| Inter-Assay |
|
| Intra-Assay |
|
| Spike Recovery |
|
| Sample Volume |
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
No significant interference observed with available related molecules. |
Packaging, Storage & Formulations
| Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Cochlin DuoSet ELISA, 5 Plate
Background
Cochlin is the major protein component of inner ear extracellular matrix. It contains one LCCL/FCH and two VWF-A domains, any of which may be deleted by alternate splicing. Cochlin is a target of IFN- producing T cells in autoimmune sensorineural hearing loss (ASNHL). Cochlin is upregulated in glaucoma and promotes the aggregation of trabecular meshwork cells in the eye. Point mutations in Cochlin are associated with glaucoma and the autosomal hearing loss disorder DFNA9.
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