Human Axl DuoSet ELISA, 15 Plate

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Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse orthologs of chicken c-Eyk) constitute the TAM receptor tyrosine kinase subfamily. This RTK subfamily is characterized by an extracellular domain that consists of two Ig-like motifs and two fibronectin type III motifs. These receptors bind the vitamin K-dependent protein Growth Arrest Specific Gene 6 (Gas6). Receptor activation leads to cell proliferation, migration, or the prevention of apoptosis. Cellular signaling through this family of RTKs is involved in hematopoiesis, embryonic development, tumorigenesis, and spermatogenesis.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 23. Show All 23 Publications. Collapse Publications.

Publications using DY154	Applications	Species
Xiong, Y;Wang, B;Jiao, J;Tang, M;Li, K;Jiang, R;Huang, W; Expression and clinical association of MFG-E8 and TAM receptors in diabetic patients with different stages of microvascular complication: An experimental study Medicine 2023-11-03 [PMID: 37933040] (Human)		Human
Nordbø, OP;Landolt, L;Eikrem, Ø;Scherer, A;Leh, S;Furriol, J;Apeland, T;Mydel, P;Marti, HP; Transcriptomic analysis reveals partial epithelial-mesenchymal transition and inflammation as common pathogenic mechanisms in hypertensive nephrosclerosis and Type 2 diabetic nephropathy Physiological reports 2023-10-01 [PMID: 37813528] (Human)		Human
D Apostolo, D D'Onghia, S Tonello, R Minisini, A Baricich, C Gramaglia, F Patrucco, P Zeppegno, A Acquaviva, PE Balbo, LM Castello, G Cappellano, A Chiocchett, C Gerevini, M Giordano, F Laaguid, M Manfredi, D Raineri, C Rigamonti, R Rolla, V Romano, M Confalonie, P Savoia, E Zavattaro, M Pirisi, B Ruaro, PP Sainaghi, M Bellan, No-More CO Decreased Gas6 and sAxl Plasma Levels Are Associated with Hair Loss in COVID-19 Survivors International Journal of Molecular Sciences, 2023-03-26;24(7):. 2023-03-26 [PMID: 37047229] (Human)		Human
S Tonello, M Rizzi, E Matino, M Costanzo, GF Casciaro, A Croce, E Rizzi, E Zecca, A Pedrinelli, V Vassia, R Landi, M Bellan, LM Castello, R Minisini, VR Mallela, D D'Onghia, GC Avanzi, M Pirisi, D Lilleri, PP Sainaghi Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 Patients Disease Markers, 2022-04-29;2022(0):1568352. 2022-04-29 [PMID: 35531477] (Human)		Human
U Schött, C Augustsson, L Lilover, CU Nilsson, L Walther-St, T Kander Vitamin K Effects on Gas6 and Soluble Axl Receptors in Intensive Care Patients: An Observational Screening Study Nutrients, 2021-11-16;13(11):. 2021-11-16 [PMID: 34836355] (Human)		Human
J Huckriede, SB Anderberg, A Morales, F de Vries, M Hultström, A Bergqvist, JT Ortiz-Pére, JW Sels, K Wichapong, M Lipcsey, M van de Pol, A Larsson, T Luther, C Reutelings, PG de Frutos, R Frithiof, GAF Nicolaes Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients Scientific Reports, 2021-08-03;11(1):15701. 2021-08-03 [PMID: 34344929] (Human)		Human
J Vullings, JP Vago, CEJ Waterborg, RM Thurlings, MI Koenders, PLEM van Lent, PM van der Kr, FA Amaral, FAJ van de Loo Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis J Immunol Res, 2020-09-11;2020(0):9690832. 2020-09-11 [PMID: 32964059] (Human)		Human
K Lashkari, GC Teague, U Beattie, J Betts, S Kumar, MM McLaughlin, FJ López Plasma biomarkers of the amyloid pathway are associated with geographic atrophy secondary to age-related macular degeneration PLoS ONE, 2020-08-07;15(8):e0236283. 2020-08-07 [PMID: 32764794] (Human)		Human
SJ Wang, R Li, TSC Ng, G Luthria, MJ Oudin, M Prytyskach, RH Kohler, R Weissleder, DA Lauffenbur, MA Miller Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy Sci Adv, 2020-05-22;6(21):eaaz8521. 2020-05-22 [PMID: 32494745] (Human)		Human
M Bellan, A Dimagli, C Piccinino, A Giubertoni, A Ianniello, F Grimoldi, M Sguazzotti, A Nerviani, M Barini, A Carriero, C Smirne, ME Burlone, C Rigamonti, R Minisini, L Salmi, MN Barbaglia, LM Castello, D Sola, P Marino, GC Avanzi, M Pirisi, PP Sainaghi Role of Gas6 and TAM Receptors in the Identification of Cardiopulmonary Involvement in Systemic Sclerosis and Scleroderma Spectrum Disorders Dis. Markers, 2020-05-12;2020(0):2696173. 2020-05-12 [PMID: 32454903] (Human)		Human
CT Chen, PC Peng, T Tsai, HF Chien, MJ Lee A Novel Treatment Modality for Malignant Peripheral Nerve Sheath Tumor Using a Dual-Effect Liposome to Combine Photodynamic Therapy and Chemotherapy Pharmaceutics, 2020-04-02;12(4):. 2020-04-02 [PMID: 32252313] (Mouse)		Mouse
K Flem-Karls, M Nyakas, IN Farstad, E McFadden, P Wernhoff, KD Jacobsen, VA Flørenes, GM Mælandsmo Soluble AXL as a marker of disease progression and survival in melanoma PLoS ONE, 2020-01-09;15(1):e0227187. 2020-01-09 [PMID: 31917795] (Human)		Human
A Tutusaus, E de Gregori, B Cucarull, H Cristóbal, C Aresté, I Graupera, M Coll, A Colell, G Gausdal, JB Lorens, P García de, A Morales, M Marí A FUNCTIONAL ROLE OF GAS6/TAM IN NON-ALCOHOLIC STEATOHEPATITIS PROGRESSION IMPLICATES AXL AS THERAPEUTIC TARGET Cell Mol Gastroenterol Hepatol, 2019-11-02;0(0):. 2019-11-02 [PMID: 31689560] (Human)		Human
I Parodis, H Ding, A Zickert, G Cosson, M Fathima, C Grönwall, C Mohan, I Gunnarsson Serum Axl predicts histology-based response to induction therapy and long-term renal outcome in lupus nephritis PLoS ONE, 2019-02-11;14(2):e0212068. 2019-02-11 [PMID: 30742665] (Human)		Human
K Flem Karls, E McFadden, VA Flørenes, B Davidson Soluble AXL is ubiquitously present in malignant serous effusions Gynecol. Oncol., 2018-11-15;0(0):. 2018-11-15 [PMID: 30448261] (Human)		Human
J García-Luc, VI Peinado, L de Jover, R Del Pozo, I Blanco, C Bonjoch, N Coll-Bonfi, T Paul, O Tura-Ceide, JA Barberà Imbalance between endothelial damage and repair capacity in chronic obstructive pulmonary disease PLoS ONE, 2018-04-19;13(4):e0195724. 2018-04-19 [PMID: 29672621] (Human)		Human
M Kurowska-S, S Alivernini, EG Melchor, A Elmesmari, B Tolusso, C Tange, L Petricca, DS Gilchrist, G Di Sante, C Keijzer, L Stewart, C Di Mario, V Morrison, JM Brewer, D Porter, S Milling, RD Baxter, D McCarey, E Gremese, G Lemke, G Ferracciol, C McSharry, IB McInnes MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis Nat Commun, 2017-06-22;8(0):15877. 2017-06-22 [PMID: 28639625] (Human)		Human
M Dengler, K Staufer, H Huber, R Stauber, H Bantel, KH Weiss, P Starlinger, H Pock, P Klöters-Pl, DN Gotthardt, P Rauch, C Lackner, J Stift, C Brostjan, T Gruenberge, T Kumada, H Toyoda, T Tada, TS Weiss, M Trauner, W Mikulits Soluble Axl is an accurate biomarker of cirrhosis and hepatocellular carcinoma development: results from a large scale multicenter analysis Oncotarget, 2017-07-11;8(28):46234-46248. 2017-07-11 [PMID: 28526812] (Human)		Human
ADAM17 substrate release in proximal tubule drives kidney fibrosis JCI Insight, 2016-08-18;1(13):. 2016-08-18 [PMID: 27642633] (Human)		Human
CC Mok, HH Ding, M Kharboutli, C Mohan Axl, Ferritin, Insulin-Like Growth Factor Binding Protein 2, and Tumor Necrosis Factor Receptor Type II as Biomarkers in Systemic Lupus Erythematosus Arthritis Care Res (Hoboken), 2016-07-28;68(9):1303-9. 2016-07-28 [PMID: 26749069] (Human)		Human
Johansson , Gunnar, Peng , Po-Chun, Huang , Po-Yuan, Chien , Hsiung-F, Hua , Kuo-Tai, Kuo , Min-Lian, Chen , Chin-Tin, Lee , Ming-Jen Soluble AXL: a possible circulating biomarker for neurofibromatosis type 1 related tumor burden. PLoS ONE, 2014-12-31;9(12):e115916. 2014-12-31 [PMID: 25551830] (Human)		Human
Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 2009-11-19;4(11):e7916. 2009-11-19 [PMID: 19936259] (Human)		Human
Scutera S, Fraone T, Musso T, Cappello P, Rossi S, Pierobon D, Orinska Z, Paus R, Bulfone-Paus S, Giovarelli M Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway. J. Immunol., 2009-08-05;183(5):3004-13. 2009-08-05 [PMID: 19657094] (Human)		Human
Show All 23 Publications. Collapse Publications.

Array DY154

• Axl Antibodies
• Axl Antibody Pair
• Axl Lysate
• Axl Proteins
• Axl ELISAs
• Axl Proteins and Enzymes