Axl Products

Description

Axl is encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Bioinformatics

Entrez	558 Human
Uniprot	AAA61243 Human AAH32229 Human AAH32229.1 Human NM_021913 Human NP_001690 Human NP_001690.2 Human NP_068713 Human NP_068713.2 Human P30530 Human
Product By Gene ID	558
Alternate Names	AXL oncogene AXL receptor tyrosine kinase AXL transforming sequence/gene EC 2.7.10 EC 2.7.10.1 JTK11 tyrosine-protein kinase receptor UFO UFOoncogene AXL

Research Areas for Axl

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Phospho-Specific

Related Axl Blog Posts

Check out the latest blog posts on Axl.

Microglia: pruning shears for homeostatic maintenance in the brain By Jennifer Sokolowski, MD, PhD.Microglia play a critical role in pruning neurons and synapses during homeostatic maintenance in the adult brain.1 A recent study by Ayata et al. (2018) identified regional differe...    Read more.

Read more Axl related blogs.