Hsp47 Antibody (950806) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Heat Shock Protein 47 (HSP47), also known as Serpin-H1/CBP1/CBP2, is localized to endoplasmic reticulum (ER), where it is a collagen-specific molecular chaperone.  In the ER, HSP47 interacts with and stabilizes correctly-folded procollagen. Nucleotide polymorphisms may be associated with preterm birth and Osteogenesis Imperfecta type X.  Serpin-H1 is up-regulated in several cancers including squamous cell carcinoma, breast and prostate carcinomas.  Expression in tumors drives malignant growth and invasion by enhancing deposition of extracellular matrix proteins.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 3 of 3.

Publications using MAB9166	Applications	Species
Ramani K, Mavila N, Abeynayake A et al. Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models eLife 2022-10-04 [PMID: 36193675]
Ramani K, Mavila N, Abeynayake A et al. Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models eLife 10/4/2022 [PMID: 36193675]
S Li, M Garcia, RL Gewiss, W Winuthayan Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo PLoS Genet., 2017-04-17;13(4):e1006743. 2017-04-17 [PMID: 28414719] (Western Blot, Mouse)	Western Blot	Mouse

Array MAB9166

• Hsp47 Antibodies
• Hsp47 ELISA Kits
• Hsp47 Lysate
• Hsp47 Proteins
• Hsp47 Proteins and Enzyme