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Histone Deacetylase 4/HDAC4 Antibody (9A6E2)

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Western Blot: Histone Deacetylase 4/HDAC4 Antibody (9A6E2) [NBP3-15463] - Western blot analysis of extracts of various cell lines, using Histone Deacetylase 4/HDAC4 Rabbit mAb (NBP3-15463) at 1:1000 dilution. Secondary ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
9A6E2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Histone Deacetylase 4/HDAC4 Antibody (9A6E2) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Histone Deacetylase 4/HDAC4 (P56524). MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQL
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HDAC4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:500

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Histone Deacetylase 4/HDAC4 Antibody (9A6E2)

  • HA6116
  • HD4EC 3.5.1.98
  • HDAC4
  • HDAC-A
  • HDACABDMR
  • Histone Deacetylase 4
  • histone deacetylase A
  • KIAA0288AHO3

Background

Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HDAC4