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Histamine H2R Antibody

Images

 
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human prostate shows strong cytoplasmic positivity in smooth muscle cells.
Immunohistochemistry-Paraffin: Histamine H2R Antibody [NBP1-86082] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Histamine H2R Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HRH2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
IHC-P reported in scientific literature (PMID: 26907350). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Histamine H2R Recombinant Protein Antigen (NBP1-86082PEP)
Reviewed Applications
Read 2 Reviews rated 4
using
NBP1-86082 in the following applications:

Publications
Read Publication using
NBP1-86082 in the following applications:

Reactivity Notes

Mouse reactivity reported in the scientific literature (PMID: 26907350).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Histamine H2R Antibody

  • Gastric Receptor 1
  • Gastric receptor I
  • H2R
  • HH2R
  • Histamine H2 R
  • histamine H2 receptor
  • Histamine H2R
  • histamine receptor H2
  • HRH2

Background

HRH2 encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Histamine H2R Antibody (NBP1-86082)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.


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IHC-P
(1)
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Filter By Species
Mouse
(1)
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Reviews for Histamine H2R Antibody (NBP1-86082) (2) 42

Average Rating: 4
(Based on 2 reviews)
We have 2 reviews tested in 2 species: Human, Rat.

Reviews using NBP1-86082:
Filter by Applications
ICC
(1)
IHC-P
(1)
All Applications
Filter by Species
Human
(1)
Rat
(1)
All Species
Images Ratings Applications Species Date Details
Immunocytochemistry Histamine H2R NBP1-86082
Enlarge
4
reviewed by:
Verified Customer
ICC Human 06/05/2018
View

Summary

ApplicationImmunocytochemistry
Sample TestedHuman Hepatoblastoma
SpeciesHuman
Lot0

Comments

Comments1:200 dilution
Overnight , 4C
No blocking
Permeabilized by 1% Triton-X100
Immunohistochemistry-Paraffin Histamine H2R NBP1-86082
Enlarge
4
reviewed by:
Mozhdeh Sojoodi
IHC-P Rat 05/04/2018
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedLiver
SpeciesRat
LotNBP1-86082

Comments

Comments1:100 dilution
Incubation:Overnight, 4 C
Citrate buffer Antigen retrieval

Product General Protocols

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FAQs for Histamine H2R Antibody (NBP1-86082) (0)

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Secondary Antibodies

 

Isotype Controls

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Recent Reviews

4
5
0
4
2
3
0
2
0
1
0

Verified Customer
06/05/2018
Application: ICC
Species: Human

Mozhdeh Sojoodi
05/04/2018
Application: IHC-P
Species: Rat

Bioinformatics

Gene Symbol HRH2