Histamine H2R Products

Description

HRH2 encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Bioinformatics

Entrez	3274 Human
Uniprot	NP_001124527.1 Human NP_001124527.1 Human NP_071640 Human NP_071640.1 Human NP_071640.1 Human P25021 Human
Product By Gene ID	3274
Alternate Names	gastric receptor 1 Gastric receptor I H2R HH2R histamine H2 receptor histamine receptor H2

Research Areas for Histamine H2R

Find related products by research area and learn more about each of the different research areas below.

GPCR
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