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Cholecystokinin-B R/CCKBR Antibody

Images

 
Western Blot: Cholecystokinin-B R/CCKBR Antibody [NB100-2803] - (0.5ug/ml) staining of Mouse Pancreas lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.
Immunohistochemistry: Cholecystokinin-B R/CCKBR Antibody [NB100-2803] - Negative Control showing staining of paraffin embedded Human Pancreas, with no primary antibody.
Immunohistochemistry: Cholecystokinin-B R/CCKBR Antibody [NB100-2803] - (6ug/ml) staining of paraffin embedded Human Pancreas. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Cholecystokinin-B R/CCKBR Antibody Summary

Immunogen
Peptide with sequence C-FDGDSDSDSQSRVRNQ corresponding to internal region according to NP_795344.1.
Predicted Species
Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCKBR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 4-6 ug/ml
  • Immunohistochemistry-Paraffin 4-6 ug/ml
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 0.3 - 1 ug/ml
Application Notes
WB: Approx 48-50kDa band observed in Mouse Pancreas lysates (calculated MW of 49.2kDa according to Mouse NP_031653.1). Primary incubation 1 hour at room temperature. br/> IHC-P: Human pancreas shows staining of the islets of langerhans.
Theoretical MW
48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NB100-2803.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cholecystokinin-B R/CCKBR Antibody

  • CCK2 receptor
  • CCK2R
  • CCK2-R
  • CCK-B receptor
  • CCK-B
  • CCKBR
  • CCK-BR
  • CCKRB
  • cholecystokinin B receptor
  • Cholecystokinin-2 receptor
  • Cholecystokinin-B R
  • cholecystokinin-B receptor/gastrin receptor
  • CholecystokininBR
  • Cholecystokinin-BR
  • GASR
  • Gastrin Receptor
  • gastrin/cholecystokinin type B receptor

Background

CCKBR is a receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cholecystokinin-B R/CCKBR Antibody (NB100-2803)(2)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCKBR
Entrez
Uniprot