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HIST1H2BC Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: HIST3H2BB Antibody [NBP2-31878] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
Immunohistochemistry: HIST3H2BB Antibody [NBP2-31878] - Staining of human kidney shows moderate nuclear positivity in cells in tubules.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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HIST1H2BC Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: PDPSKSAPAPKKGSKKAVTKAQKKD
Predicted Species
Mouse (92%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HIST1H2BC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
HIST1H2BC Recombinant Protein Antigen (NBP2-31878PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for HIST1H2BC Antibody

  • H2B histone family, member K
  • H2B/a
  • H2B/g
  • H2B/kH2B/h
  • H2BFA
  • H2BFG
  • H2BFH
  • H2BFKH2B/l
  • H2BFL
  • HIST1H2BC
  • HIST1H2BE
  • HIST1H2BF
  • HIST1H2BG
  • histone 1, H2bi
  • histone cluster 1, H2bi
  • histone H2B type 1-C/E/F/G/I
  • Histone H2B.1 A
  • Histone H2B.a
  • Histone H2B.g
  • Histone H2B.h
  • Histone H2B.k
  • Histone H2B.l

Background

HIST1H2BC is 126 amino acids long, weighs approximately 14 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including systemic lupus erythematosus, lupus erythematosus, hemochromatosis, and immunodeficiency. HIST1H2BC has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the histone modification, signal transduction of Activin A, telomere maintenance, nucleosome assembly, cell cycle, and systemic lupus erythematosus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol HIST1H2BC