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Histone H2AE [Hydroxy Tyr39] Antibody (2J2Q7)

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clone
2J2Q7
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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Histone H2AE [Hydroxy Tyr39] Antibody (2J2Q7) Summary

Immunogen
A synthetic hydroxylated peptide around Y39 of human Histone H2AE (P04908).

Sequence:
KGNYS
Modification
Hydroxy Tyr39
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HIST1H2AE
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Recommended starting concentration is 1 ug/mL
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 1:500 - 1:2000
Theoretical MW
14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Histone H2AE [Hydroxy Tyr39] Antibody (2J2Q7)

  • H2A histone family, member M
  • H2A/m
  • H2AFA
  • H2AFMHistone H2A/m
  • HIST1H2AE
  • histone 1, H2ab
  • histone cluster 1, H2ab
  • histone H2A type 1-B/E
  • Histone H2A.2
  • Histone H2A/a

Background

Histone H2AE is 124 amino acids long, weighing approximately 13 kDa, and is part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes and is a core component of the nucleosome. Current studies are being done on several diseases and disorders including riddle syndrome, systemic lupus erythematosus, lupus srythematosus, and immunodeficiency. This protein has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the proteasome degradation, nucleosome assembly, cell cycle, and systemic lupus erythematosus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-33534

Research Areas for Histone H2AE Antibody (NBP3-33534)

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Bioinformatics

Gene Symbol HIST1H2AE