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HIST1H2AG Antibody (CL5039)

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Western Blot: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Analysis of purified human recombinant histone H2A, H2A.X, H2A.Z, mH2A.1, mH2A.2, H2B, H3 and H4.
Immunohistochemistry: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Staining of human cerebral cortex shows moderate to strong nuclear immunoreactivity in neuronal and glial cells.
Western Blot: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Western blot analysis in human cell line K562.
Immunohistochemistry-Paraffin: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Staining of human testis shows strong nuclear immunoreactivity in cells in seminiferous tubules.
Immunohistochemistry-Paraffin: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Staining of human small intestine shows strong nuclear immunoreactivity in glandular cells as well as in cells in lamina propria.
Immunohistochemistry-Paraffin: HIST1H2AG Antibody (CL5039) [NBP2-61151] - Staining of human kidney shows strong nuclear positivity in renal tubules and in glomerular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
CL5039
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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HIST1H2AG Antibody (CL5039) Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to the following amino acid sequence:RSSRAGLQFPVGRVHR
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HIST1H2AG
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for HIST1H2AG Antibody (CL5039)

  • H2A histone family, member P
  • H2A.1
  • H2A.1b
  • H2A/p
  • H2AFC
  • H2AFD
  • H2AFI
  • H2AFN
  • H2AFP
  • HIST1H2AI
  • HIST1H2AK
  • HIST1H2AL
  • HIST1H2AM
  • histone 1, H2ag
  • histone cluster 1, H2ag
  • histone H2A type 1
  • Histone H2A/p
  • pH2A/f

Background

HIST1H2AG is 130 amino acids long, weighs approximately 14 kDa, and the gene codes for a part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Current studies are being done on several diseases and disorders including riddle syndrome, systemic lupus erythematosus, lupus erythematosus, schizophrenia, and immunodeficiency. HIST1H2AG has also been shown to have interactions with IL33, RYBP, YWHAZ, YWHAQ, and SAP30 in pathways such as the histone modification, signal transduction of Activin A, and systemic lupus erythematosus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HIST1H2AG