Hepcidin Antimicrobial Peptide Antibody

The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-36960	Applications	Species
Ward DG, Roberts K, Brookes MJ et al. Increased hepcidin expression in colorectal carcinogenesis. World J Gastroenterol 2008-03-07 [PMID: 18322945]

Array NBP1-36960

• Hepcidin Antimicrobial Peptide Antibodies
• Hepcidin Antimicrobial Peptide ELISA Kits
• Hepcidin Antimicrobial Peptide Lysate
• Hepcidin Antimicrobial Peptide Protein
• Hepcidin Antimicrobial Peptide ELISAs