TfR2 Antibody (353816) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Transferrin Receptor 2 (TfR2) is an iron-binding protein that is homologous to the transferrin receptor. Lack of active TfR2 has been associated with a rare form of hemochromatosis. The TfR2 alpha isoform is a type 2 transmembrane protein that is expressed in the liver and modulates hepcidin production in response to iron. It forms a 215 kDa disulfide-linked homodimer that is presumably glycated. The TfR2 beta isoform lacks the intracellular, transmembrane and part of the extracellular regions and is expressed ubiquitously. The extracellular portion of human TfR2 shares 86% aa identity with mouse.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 4 of 4.

Publications using MAB3120	Applications	Species
Y He, X Zhang, I Flais, P Svenningss Decreased Prosaposin and Progranulin in the Cingulate Cortex Are Associated with Schizophrenia Pathophysiology International Journal of Molecular Sciences, 2022-10-10;23(19):. 10/10/2022 [PMID: 36233357]
Xiao J, Yao J, Jia L et al. Autophagy activation and photoreceptor survival in retinal detachment Experimental eye research 2/18/2021 [PMID: 33609513]
Ross BX, Choi J, Yao J et al. Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment Invest. Ophthalmol. Vis. Sci. 5/11/2020 [PMID: 32460314]
Jing Zhou, Yunqing Wen, Liang She, Ya-nan Sui, Lu Liu, Linda J. Richards et al. Axon position within the corpus callosum determines contralateral cortical projection Proceedings of the National Academy of Sciences 2013-07-16 [PMID: 23812756]

Array MAB3120

• TfR2 Antibodies
• TfR2 ELISA Kits
• TfR2 Lysate
• TfR2 Protein
• TfR2 Proteins and Enzyme