HBS1L Antibody

HBS1L encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 2 of 2.

Publications using NBP1-85123	Applications	Species
Chumchuen S, Sripichai O, Jearawiriyapaisarn N et al. Induction of fetal hemoglobin: Lentiviral shRNA knockdown of HBS1L in ?0-thalassemia/HbE erythroid cells PloS one 2023-03-08 [PMID: 36888630] (Western Blot, Human)	Western Blot	Human
Ahmad Y, Boisvert FM, Lundberg E et al. Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. Mol Cell Proteomics 2012-03-01 [PMID: 22002106]

Array NBP1-85123

• HBS1L Antibodies
• HBS1L Lysate
• HBS1L Proteins