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GSTZ1 Antibody

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Western Blot: GSTZ1 Antibody [NBP1-83320] - Analysis in human liver tissue.
Immunocytochemistry/ Immunofluorescence: GSTZ1 Antibody [NBP1-83320] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
Western Blot: GSTZ1 Antibody [NBP1-83320] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18Lane 2: Human cell line RT-4Lane 3: Human cell line U-251MG spLane 4: Human plasma (IgG/HSA depleted)Lane 5: Human liver ...read more
Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.
Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and in glomeruli.
Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: GSTZ1 Antibody [NBP1-83320] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts and leydig cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GSTZ1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NLSVLKQVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELRA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GSTZ1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:100-1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
GSTZ1 Protein (NBP1-83320PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GSTZ1 Antibody

  • EC 2.5.1.18
  • EC 5.2.1.2
  • glutathione S-alkyltransferase
  • glutathione S-aralkyltransferase
  • Glutathione S-transferase zeta 1
  • glutathione transferase zeta 1
  • GSTZ1-1maleylacetoacetate isomerase
  • MAAIglutathione S-aryltransferase
  • MAI
  • maleylacetone isomerase
  • MGC2029
  • S-(hydroxyalkyl)glutathione lyase

Background

GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GSTZ1