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Granulysin Antibody - BSA Free

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Analysis in human spleen and pancreas tissues. Corresponding Granulysin RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.
Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Staining of human endometrium strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Staining of human lymph node shows strong cytoplasmic positivity in a small subset of non-germinal center cells.
Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: Granulysin Antibody [NBP2-38839] - Staining of human skeletal muscle no positivity in myocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Validated by:
       

Orthogonal Strategies

 

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Granulysin Antibody - BSA Free Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: RLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GNLY
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Granulysin Protein (NBP2-38839PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Granulysin Antibody - BSA Free

  • D2S69Elymphocyte-activation gene 2
  • GNLY
  • Granulysin
  • LAG2
  • LAG-2
  • Lymphokine LAG-2
  • Lymphokine
  • NKG5
  • NKG5519
  • Protein NKG5
  • TLA519
  • TLA519T-cell activation protein 519
  • T-lymphocyte activation gene 519

Background

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GNLY
Uniprot