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Glucagon Antibody (49) - BSA Free

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Glucagon Antibody (49) - BSA Free [NBP2-23591]

Product Details

Summary
Reactivity MaSpecies Glossary
Applications WB, ELISA
Clone
49
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Glucagon Antibody (49) - BSA Free Summary

Immunogen
Synthetic GLP-1(9-18)
Epitope
The free N-terminus of GLP-1(9-36)amide and GLP-1(9-37)
Specificity
Clone 49 binds human GLP-1(9-36)amide Based on inhibition ELISA, Clone 49 cross-reacts 3% with GLP-1(7-36)amide
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GCG
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
Application Notes
ELISA: NBP2-23591 binds free GLP-1(9-36)amide in solution. In a sandwich ELISA NBP2-23591 (as capture antibody) forms a pair with NBP2-23505 (as biotinylated detection antibody) in order to measure "degraded GLP-1" (the GLP-1 metabolite (GLP-1(9-36)amide)). WB: NBP2-23591 can be used in Western blotting.
Publications
Read Publications using NBP2-23591.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
10mM Phosphate (pH 7.4) and 0.5M NaCl
Preservative
0.9% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Glucagon Antibody (49) - BSA Free

  • GCG
  • glicentin-related polypeptide
  • GLP1
  • GLP-1
  • Glucagon
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • GRPP

Background

Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glucagon Antibody (NBP2-23591)(2)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GCG