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Glucagon Antibody (49) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity MaSpecies Glossary
Applications WB, ELISA
Clone
49
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700

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Glucagon Antibody (49) [Alexa Fluor® 700] Summary

Immunogen
Synthetic GLP-1(9-18)
Epitope
The free N-terminus of GLP-1(9-36)amide and GLP-1(9-37)
Specificity
Clone 49 binds human GLP-1(9-36)amide Based on inhibition ELISA, Clone 49 cross-reacts 3% with GLP-1(7-36)amide
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GCG
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mammal

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Glucagon Antibody (49) [Alexa Fluor® 700]

  • GCG
  • glicentin-related polypeptide
  • GLP1
  • GLP-1
  • Glucagon
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • GRPP

Background

The protein encoded by the Glucagon gene is actually a preproprotein that is cleaved into four distinct mature peptides. One ofthese, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulatingglycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signallingpathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promotenutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an activeenteroglucagon. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GCG