GIP Antibody (911205) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones. GIP, together with glucagon-like peptide-1 (GLP-1), belongs to the group of metabolic hormones called incretins that stimulate a decrease in blood glucose levels. GIP is derived from a 153-amino acid pro-protein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide.  Engagement of Gastric inhibitory polypeptide receptors (GIPR) by GIP on pancreatic beta cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose.

GIP (1-39) is an endogenous truncated form of GIP that has been shown to be more potent in stimulating insulin secretion from rat pancreatic islets.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC.

Showing Publication 1 - 1 of 1.

Publication using MAB8864	Applications	Species
T Masaki, Y Kodera, M Terasaki, K Fujimoto, T Hirano, M Shichiri GIP_HUMAN[22-51] is a new proatherogenic peptide identified by native plasma peptidomics Scientific Reports, 2021-07-14;11(1):14470. 2021-07-14 [PMID: 34262109] (IHC, Human)	IHC	Human

Array MAB8864

• GIP Antibodies
• GIP ELISA Kits
• GIP Lysate
• GIP Proteins