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GITR/TNFRSF18 Antibody (108619) [PE/Atto594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
108619
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Atto594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB5241U-100UG
Alexa Fluor 405
FAB5241V-100UG
Alexa Fluor 488
FAB5241G-100UG
Alexa Fluor 532
FAB5241X
Alexa Fluor 594
FAB5241T-100UG
Alexa Fluor 647
FAB5241R-100UG
Alexa Fluor 700
FAB5241N-100UG
Alexa Fluor 750
FAB5241S-100UG
Allophycocyanin
FAB5241A
Allophycocyanin/Cy7
FAB5241APCCY7
Biotin
FAB5241B
DyLight 350
FAB5241D
DyLight 405
FAB5241E
DyLight 488
FAB5241K
DyLight 550
FAB5241L
DyLight 594
FAB5241M
DyLight 650
FAB5241W
DyLight 680
FAB5241Y
DyLight 755
FAB5241Z
HRP
FAB5241H
Janelia Fluor 525
FAB5241JF525
Janelia Fluor 549
FAB5241I
Janelia Fluor 646
FAB5241J
Janelia Fluor 669
FAB5241JF669
PE/Cy5.5
FAB5241PECY55
PE/Cy7
FAB5241PECY7
Unconjugated
MAB5241
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB5241
Carrier Free
FAB5241A
Carrier Free
MAB5241
Carrier Free
MAB5241-SP
Carrier Free
FAB5241V-100UG
Carrier Free
FAB5241U-100UG
Carrier Free
FAB5241T-100UG
Carrier Free
FAB5241S-100UG
Carrier Free
FAB5241R-100UG
Carrier Free
FAB5241N-100UG
Carrier Free
FAB5241G-100UG
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GITR/TNFRSF18 Antibody (108619) [PE/Atto594] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse GITR/TNFRSF18
Met1-His153
Accession # O35714
Specificity
Detects mouse GITR/TNFRSF18 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4‑1BB, recombinant mouse (rm) CD27, rmCD30, rmEDAR, rmFas, rhGITR, rhHVEM, rmRANK, rhTROY, and rmTNF R1 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
TNFRSF18
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for GITR/TNFRSF18 Antibody (108619) [PE/Atto594]

  • Activation-inducible TNFR family receptor
  • AITR
  • AITRTNF receptor superfamily activation-inducible protein
  • CD357 antigen
  • CD357
  • GITR
  • GITR-D
  • GITRtumor necrosis factor receptor superfamily member 18
  • Glucocorticoid-induced TNFR-related protein
  • TNFRSF18
  • tumor necrosis factor receptor superfamily, member 18

Background

GITR is encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF18