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FIZZ1/RELM alpha Antibody [Unconjugated]

 (7 Publications)
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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
Biotin
BAF1523
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Catalog# & Formulation Size Price
Carrier Free
AF1523-SP
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FIZZ1/RELM alpha Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant mouse FIZZ1/RELM alpha
Asp24-Ser111
Accession # Q9EP95
Specificity
Detects mouse FIZZ1/RELM alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross‑reactivity with recombinant mouse Resistin is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
RETNLA
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF1523 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FIZZ1/RELM alpha Antibody [Unconjugated]

  • 1810019L16Rik
  • FIZZ1
  • Fizz-1
  • HIMF
  • RELM alpha
  • RELMa
  • RELMalpha
  • RELM-alpha
  • Retnla resistin like alpha
  • RETNLA
  • RETNLB
  • Xcp2

Background

RELM alpha , also known as ‘found in inflammatory zone 1’ (FIZZ1) belongs to the RELM1/FIZZ family of cysteine rich secretory proteins. RELM alpha is most abundantly expressed in white adipose tissue but not in preadipocytes nor 3T3-L1 adipocytes. RELM alpha expression is also detected in heart, lung, and tongue (1).
  1. Steppan, C.M. et al. (2001) Proc. Natl. Acad. Sci. USA 98:502.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FIZZ1/RELM alpha Antibody (AF1523)(7)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Complex Species Category.

We have publications tested in 3 applications: ICC, IHC-P, Western Blot.


Filter By Application
ICC
(1)
IHC-P
(3)
Western Blot
(3)
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Filter By Species
Human
(1)
Mouse
(3)
Rat
(1)
Complex Species Category
(1)
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Showing Publications 1 - 7 of 7.
Publications using AF1523 Applications Species
Q Lin, S Kumar, U Kariyawasa, X Yang, W Yang, JT Skinner, WD Gao, RA Johns Human Resistin Induces Cardiac Dysfunction in Pulmonary Hypertension Journal of the American Heart Association, 2023-03-16;12(6):e027621. 3/16/2023 [PMID: 36927008]
A Dumigan, O Cappa, B Morris, J Sá Pessoa, R Calderon-G, G Mills, R Lancaster, D Simpson, A Kissenpfen, JA Bengoechea In vivo single-cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection Embo Molecular Medicine, 2022-11-07;0(0):e16888. 2022-11-07 [PMID: 36337046] (Western Blot, Complex Species Category) Western Blot Complex Species Category
Matthew E Long MEK1/2 Inhibition Promotes Macrophage Reparative Properties J. Immunol, 2016-12-21;0(0):. 2016-12-21 [PMID: 28003382] (Western Blot, Mouse) Western Blot Mouse
Angelini D, Su Q, Yamaji-Kegan K, Fan C, Skinner J, Poloczek A, El-Haddad H, Cheadle C, Johns R Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling. Respir Res, 2013-01-04;14(0):1. 2013-01-04 [PMID: 23289668] (IHC-P, Western Blot, Mouse) IHC-P, Western Blot Mouse
Fan C, Johns B, Su Q, Kolosova I, Johns R Choosing the right antibody for resistin-like molecule (RELM/FIZZ) family members. Histochem Cell Biol, 2012-10-18;0(0):. 2012-10-18 [PMID: 23076260] (ICC, Human) ICC Human
Yamaji-Kegan K, Su Q, Angelini DJ, Myers AC, Cheadle C, Johns RA Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism. J. Immunol., 2010-10-01;185(9):5539-48. 2010-10-01 [PMID: 20889544] (IHC-P, Mouse) IHC-P Mouse
Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, Champion HC, Crow MT, Johns RA Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELM{alpha}) induces the vascular and hemodynamic changes of pulmonary hypertension. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-01-09;296(4):L582-93. 2009-01-09 [PMID: 19136574] (IHC-P, Rat) IHC-P Rat

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RETNLA
Uniprot