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FCRL3/FcRH3 Antibody (H5) - BSA Free

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Flow Cytometry: FCRL3/FcRH3 Antibody (H5) [NBP3-11831] - Multicolor surface staining of human lymphocytes stained using anti-human CD19 (LT19) APC antibody (10 ul reagent / 100 ul of peripheral whole blood) and ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
H5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

FCRL3/FcRH3 Antibody (H5) - BSA Free Summary

Additional Information
Clone H5 was used by HLDA to establish CD designation.
Immunogen
DNA-immunization followed by a boost with FCRL3/FcRH3 transfected cells
Specificity
The mouse monoclonal antibody H5 recognizes an epitope within extracellular part of FCRL3/FcRH3, a transmembrane glycoprotein expressed mainly on NK cells, and T and B cell subsets.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FCRL3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1-4 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
0.9% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for FCRL3/FcRH3 Antibody (H5) - BSA Free

  • CD307c
  • Fc receptor homolog 3
  • Fc receptor-like 3
  • Fc receptor-like protein 3
  • FcRH3
  • FCRL3
  • fcR-like protein 3
  • hIFGP3
  • IFGP3
  • immunoglobulin superfamily receptor translocation associated protein 3
  • IRTA3
  • SPAP2

Background

FCRL3/FcRH3 is a type I transmembrane glycoprotein of the Fc receptor family. It contains both ITAM and ITIM motifs in its cytoplasmic domain. FCRL3/FcRH3 is expressed on the surface of NK cells, and T, Treg, B and plasma cell subsets. It seems to play a role in the regulation of immune response. Defects in FCRL3/FcRH3 function can result in autoimmune diseases, e.g. rheumatoid arthritis or systemic lupus erythematosus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FCRL3